{"id":13869,"date":"2018-10-16T12:59:30","date_gmt":"2018-10-16T12:59:30","guid":{"rendered":"http:\/\/horizonshemato.com\/?post_type=product&p=13869"},"modified":"2024-01-08T17:17:09","modified_gmt":"2024-01-08T17:17:09","slug":"horizons-hemato-vol-5-n2-juin-2015","status":"publish","type":"product","link":"https:\/\/horizonshemato.com\/en\/product\/horizons-hemato-vol-5-n2-juin-2015\/","title":{"rendered":"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015"},"content":{"rendered":"

Magazine au format num\u00e9rique.
\nEnvois en version papier sur demande.<\/p>","protected":false},"excerpt":{"rendered":"

Les pathologies h\u00e9morragiques constitutionnelles de\u00a0l\u2019h\u00e9mostase sont rares, mais vari\u00e9es. Au-del\u00e0 des\u00a0aspects diagnostiques partant de la symptomatologie\u00a0commune mais tr\u00e8s polymorphe qu\u2019est le syndrome\u00a0h\u00e9morragique, elles ouvrent des champs tr\u00e8s divers.\u00a0Compte tenu de l\u2019histoire, ces pathologies sont\u00a0rarement prises en charge directement dans les services\u00a0d\u2019h\u00e9matologie clinique et les centres de traitement de\u00a0maladies h\u00e9morragiques sont le plus souvent rattach\u00e9s\u00a0\u00e0 des laboratoires sp\u00e9cialis\u00e9s en h\u00e9mostase, mais aussi\u00a0\u00e0 des services de p\u00e9diatrie, de m\u00e9decine interne\u2026\u00a0Un laboratoire d\u2019h\u00e9matologie biologique, et\u00a0plus sp\u00e9cifiquement de biologie sp\u00e9cialis\u00e9e\u00a0de l\u2019h\u00e9mostase, reste la colonne vert\u00e9brale\u00a0indispensable \u00e0 toute structure de prise en charge\u00a0diagnostique et th\u00e9rapeutique de ces maladies.\u00a0L\u2019h\u00e9mostase clinique est en effet le prototype\u00a0d\u2019une discipline transversale clinico-biologique,\u00a0o\u00f9 la s\u00e9paration entre clinique et biologique\u00a0est artificielle et d\u00e9nu\u00e9e se sens.\u00a0Nous avons voulu dans ce num\u00e9ro, donner un\u00a0aper\u00e7u des diff\u00e9rentes probl\u00e9matiques et faire\u00a0appara\u00eetre la diversit\u00e9 clinique, biologique,\u00a0g\u00e9n\u00e9tique, diagnostique de ces pathologies.\u00a0L\u2019arriv\u00e9e de technologies nouvelles, biologiques,\u00a0g\u00e9n\u00e9tiques, th\u00e9rapeutiques, la modification\u00a0ph\u00e9notypique qu\u2019on peut attendre de la pr\u00e9sentation\u00a0de la maladie, li\u00e9e aux modifications des strat\u00e9gies\u00a0th\u00e9rapeutiques de l\u2019h\u00e9mophilie au cours des deux\u00a0derni\u00e8res d\u00e9cennies vont certainement bouleverser\u00a0les approches dans les 5 \u00e0 10 ans \u00e0 venir.\u00a0La situation d\u00e9crite est celle de 2015, dans une\u00a0sp\u00e9cialit\u00e9 qui constitue donc une niche en pleine\u00a0\u00e9volution dans le monde de l\u2019h\u00e9matologie.\u00a0Enfin, un grand merci \u00e0 tous les auteurs qui, chacun sousun angle particulier, ont accept\u00e9 de participer \u00e0 ce num\u00e9ro.<\/p>\n

Thierry LAMBERT
\n<\/strong>Coordinateur du Grand Format \u00ab h\u00e9mophilie et maladies h\u00e9morragiques constitutionnelles \u00bb.
\nCentre de R\u00e9f\u00e9rence pour le Traitement des H\u00e9mophiles, Le Kremlin-Bic\u00eatre.
\nthierry.lambert@aphp.fr<\/strong><\/p>","protected":false},"featured_media":13871,"template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"product_brand":[],"product_cat":[93],"product_tag":[],"class_list":{"0":"post-13869","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-hemophilie-et-maladies-hemorragiques-constitutionnelles","8":"first","9":"instock","10":"downloadable","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"yoast_head":"\nHorizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/horizonshemato.com\/en\/product\/horizons-hemato-vol-5-n2-juin-2015\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato\" \/>\n<meta property=\"og:description\" content=\"Les pathologies h\u00e9morragiques constitutionnelles de\u00a0l\u2019h\u00e9mostase sont rares, mais vari\u00e9es. Au-del\u00e0 des\u00a0aspects diagnostiques partant de la symptomatologie\u00a0commune mais tr\u00e8s polymorphe qu\u2019est le syndrome\u00a0h\u00e9morragique, elles ouvrent des champs tr\u00e8s divers.\u00a0Compte tenu de l\u2019histoire, ces pathologies sont\u00a0rarement prises en charge directement dans les services\u00a0d\u2019h\u00e9matologie clinique et les centres de traitement de\u00a0maladies h\u00e9morragiques sont le plus souvent rattach\u00e9s\u00a0\u00e0 des laboratoires sp\u00e9cialis\u00e9s en h\u00e9mostase, mais aussi\u00a0\u00e0 des services de p\u00e9diatrie, de m\u00e9decine interne\u2026\u00a0Un laboratoire d\u2019h\u00e9matologie biologique, et\u00a0plus sp\u00e9cifiquement de biologie sp\u00e9cialis\u00e9e\u00a0de l\u2019h\u00e9mostase, reste la colonne vert\u00e9brale\u00a0indispensable \u00e0 toute structure de prise en charge\u00a0diagnostique et th\u00e9rapeutique de ces maladies.\u00a0L\u2019h\u00e9mostase clinique est en effet le prototype\u00a0d\u2019une discipline transversale clinico-biologique,\u00a0o\u00f9 la s\u00e9paration entre clinique et biologique\u00a0est artificielle et d\u00e9nu\u00e9e se sens.\u00a0Nous avons voulu dans ce num\u00e9ro, donner un\u00a0aper\u00e7u des diff\u00e9rentes probl\u00e9matiques et faire\u00a0appara\u00eetre la diversit\u00e9 clinique, biologique,\u00a0g\u00e9n\u00e9tique, diagnostique de ces pathologies.\u00a0L\u2019arriv\u00e9e de technologies nouvelles, biologiques,\u00a0g\u00e9n\u00e9tiques, th\u00e9rapeutiques, la modification\u00a0ph\u00e9notypique qu\u2019on peut attendre de la pr\u00e9sentation\u00a0de la maladie, li\u00e9e aux modifications des strat\u00e9gies\u00a0th\u00e9rapeutiques de l\u2019h\u00e9mophilie au cours des deux\u00a0derni\u00e8res d\u00e9cennies vont certainement bouleverser\u00a0les approches dans les 5 \u00e0 10 ans \u00e0 venir.\u00a0La situation d\u00e9crite est celle de 2015, dans une\u00a0sp\u00e9cialit\u00e9 qui constitue donc une niche en pleine\u00a0\u00e9volution dans le monde de l\u2019h\u00e9matologie.\u00a0Enfin, un grand merci \u00e0 tous les auteurs qui, chacun sousun angle particulier, ont accept\u00e9 de participer \u00e0 ce num\u00e9ro. Thierry LAMBERT Coordinateur du Grand Format \u00ab h\u00e9mophilie et maladies h\u00e9morragiques constitutionnelles \u00bb. Centre de R\u00e9f\u00e9rence pour le Traitement des H\u00e9mophiles, Le Kremlin-Bic\u00eatre. thierry.lambert@aphp.fr\" \/>\n<meta property=\"og:url\" content=\"https:\/\/horizonshemato.com\/en\/product\/horizons-hemato-vol-5-n2-juin-2015\/\" \/>\n<meta property=\"og:site_name\" content=\"Horizons H\u00e9mato\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-08T17:17:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"938\" \/>\n\t<meta property=\"og:image:height\" content=\"938\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/\",\"url\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/\",\"name\":\"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato\",\"isPartOf\":{\"@id\":\"https:\/\/horizonshemato.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg\",\"datePublished\":\"2018-10-16T12:59:30+00:00\",\"dateModified\":\"2024-01-08T17:17:09+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage\",\"url\":\"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg\",\"contentUrl\":\"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg\",\"width\":938,\"height\":938},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/horizonshemato.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Boutique\",\"item\":\"https:\/\/horizonshemato.com\/boutique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/horizonshemato.com\/#website\",\"url\":\"https:\/\/horizonshemato.com\/\",\"name\":\"Horizons H\u00e9mato\",\"description\":\"La revue des pratiques en h\u00e9matologie\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/horizonshemato.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/horizonshemato.com\/en\/product\/horizons-hemato-vol-5-n2-juin-2015\/","og_locale":"en_US","og_type":"article","og_title":"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato","og_description":"Les pathologies h\u00e9morragiques constitutionnelles de\u00a0l\u2019h\u00e9mostase sont rares, mais vari\u00e9es. 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Centre de R\u00e9f\u00e9rence pour le Traitement des H\u00e9mophiles, Le Kremlin-Bic\u00eatre. thierry.lambert@aphp.fr","og_url":"https:\/\/horizonshemato.com\/en\/product\/horizons-hemato-vol-5-n2-juin-2015\/","og_site_name":"Horizons H\u00e9mato","article_modified_time":"2024-01-08T17:17:09+00:00","og_image":[{"width":938,"height":938,"url":"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/","url":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/","name":"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015 - Horizons H\u00e9mato","isPartOf":{"@id":"https:\/\/horizonshemato.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage"},"image":{"@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage"},"thumbnailUrl":"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg","datePublished":"2018-10-16T12:59:30+00:00","dateModified":"2024-01-08T17:17:09+00:00","breadcrumb":{"@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#primaryimage","url":"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg","contentUrl":"https:\/\/horizonshemato.com\/wp-content\/uploads\/2018\/10\/HH-VOL5-N2.jpg","width":938,"height":938},{"@type":"BreadcrumbList","@id":"https:\/\/horizonshemato.com\/product\/horizons-hemato-vol-5-n2-juin-2015\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/horizonshemato.com\/"},{"@type":"ListItem","position":2,"name":"Boutique","item":"https:\/\/horizonshemato.com\/boutique\/"},{"@type":"ListItem","position":3,"name":"Horizons H\u00e9mato \u2013 Vol. 5 n\u00b02 \u2013 Juin 2015"}]},{"@type":"WebSite","@id":"https:\/\/horizonshemato.com\/#website","url":"https:\/\/horizonshemato.com\/","name":"Horizons H\u00e9mato","description":"La revue des pratiques en h\u00e9matologie","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/horizonshemato.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/product\/13869","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/media\/13871"}],"wp:attachment":[{"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/media?parent=13869"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/product_brand?post=13869"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/product_cat?post=13869"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/horizonshemato.com\/en\/wp-json\/wp\/v2\/product_tag?post=13869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}